Veröffentlichungen

Auswahl…

  • Hackl A, Nüsken E, Voggel J, Abo Zed SED, Binz-Lotter J, Unnersjö-Jess D, Müller C, Fink G, Bohl K, Wiesner E, Diefenhardt P, Dafinger C, Chen H, Wohlfarth M, Müller RU, Hackl MJ, Schermer B, Nüsken KD, Weber LT. The effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis. Sci Rep. 2023 Aug 29;13(1):14167. doi: 10.1038/s41598-023-41222-1. PMID: 37644089; PMCID: PMC10465485.
  • Abo Zed SED, Hackl A, Bohl K, Ebert L, Kieckhöfer E, Müller C, Becker K, Fink G, Nüsken KD, Nüsken E, Müller RU, Schermer B, Weber LT. Mycophenolic acid directly protects podocytes by preserving the actin cytoskeleton and increasing cell survival. Sci Rep. 2023 Mar 15;13(1):4281. doi: 10.1038/s41598-023-31326-z. PMID: 36922538; PMCID: PMC10017704.
  • Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand MA, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts JA, Pletz MW; TARGET Trial Investigators. Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial. Intensive Care Med. 2022 May;48(5):646-647. doi: 10.1007/s00134-022-06668-3. Erratum for: Intensive Care Med. 2022 Mar;48(3):311-321. PMID: 35303118; PMCID: PMC9050772.
  • Klein I, Boenert J, Lange F, Christensen B, Wassermann MK, Wiesen MHJ, Olschewski DN, Rabenstein M, Müller C, Lehmann HC, Fink GR, Schroeter M, Rueger MA, Vay SU. Glia from the central and peripheral nervous system are differentially affected by paclitaxel chemotherapy via modulating their neuroinflammatory and neuroregenerative properties. Front Pharmacol. 2022 Nov 2;13:1038285. doi: 10.3389/fphar.2022.1038285. PMID: 36408236; PMCID: PMC9666700
  • Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand M, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts JA, Pletz MW; TARGET Trial Investigators. Effect of therapeutic drug monitoring- based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial. Intensive Care Med. 2022 Mar;48(3):311-321. doi: 10.1007/s00134-021-06609-6. Epub 2022 Feb 1. Erratum in: Intensive Care Med. 2022 May;48(5):646-647. PMID: 35106617; PMCID: PMC8866359.
  • AWMF Ad hoc Commission In-vitro Diagnostic Medical Devices. Advisory opinion of the AWMF Ad hoc Commission In-vitro Diagnostic Medical Devices regarding in-vitro diagnostic medical devices manufactured and used only within health institutions established in the Union according to Regulation (EU) 2017/746 (IVDR). Ger Med Sci. 2021 Jun 1;19:Doc08. doi: 10.3205/000295. PMID: 34194291; PMCID: PMC8204380.
  • Wiesen MHJ, Fietz C, Jübner M, Iwersen-Bergmann S, Andresen-Streichert H, Müller C, Streichert T. Quantification of direct-acting oral anticoagulants: Application of a clinically validated liquid chromatography-tandem mass spectrometry method to forensic cases. Drug Test Anal. 2021 Feb;13(2):419-426. doi: 10.1002/dta.2930. Epub 2020 Nov 12.PMID: 32959964
  • Klein I, Wiesen MHJ, Albert V, Bobylev I, Joshi AR, Müller C, Lehmann HC. Impact of drug formulations on kinetics and toxicity in a preclinical model of paclitaxel-induced neuropathy. J Peripher Nerv Syst. 2021 Jun;26(2):216-226. doi: 10.1111/jns.12440. Epub 2021 Mar 22. PMID: 33683765.
  • Westermann I, Gastine S, Müller C, Rudolph W, Peters F, Bloos F, Pletz M, Hagel S. Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: sustained low-efficiency dialysis (SLED) and continuous veno-venous haemodialysis (CVVHD). Br J Clin Pharmacol. 2021 Apr 5. doi: 10.1111/bcp.14846. Epub ahead of print. PMID: 33818823.
  • Tahmaz V, Wiesen MHJ, Gehlsen U, Sauerbier L, Stern ME, Holtick U, Gathof B, Scheid C, Müller C, Steven P. Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease. Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):121-128. doi: 10.1007/s00417-020-04865-8. Epub 2020 Aug 19. PMID: 32812133; PMCID: PMC7790777.
  • Stemler J, Koehler P, Maurer C, Müller C, Cornely OA. Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma. Ann Hematol. 2020 Jul;99(7):1429-1440. doi: 10.1007/s00277-020-04107-1. Epub 2020 Jun 8. PMID: 32514626 Free PMC article. Review.
  • Rosen K, Wiesen MH, Oberthür A, Michels G, Roth B, Fietz C, Müller C. Drug- drug interactions in Neonatal Intensive Care Units: how to overcome a challenge. Minerva Pediatr (Torino). 2021 Apr;73(2):188-197. doi: 10.23736/S0026-4946.19.05388-X. Epub 2019 Oct 11. PMID: 31621271.
  • Weißbarth G, Wiesen MHJ, Fietz C, Streichert T, Ehren R, Weber LT, Müller C. Pharmacodynamic monitoring of mycophenolic acid therapy: Improved LC-MS/MS method for measuring inosin-5′-monophosphate dehydrogenase activity. Ther Drug Monit. 2020 Apr;42(2):282-288. doi: 10.1097/FTD.0000000000000688. PMID: 31425491
  • Benz MR, Ehren R, Kleinert D, Müller C, Gellermann J, Fehrenbach H, Schmidt H, Weber LT. Generation and validation of a limited sampling strategy to monitor mycophenolic acid exposure in children with nephrotic syndrome. Ther Drug Monit. 2019 Aug 14. doi: 10.1097/FTD.0000000000000671. [Epub ahead of print] PubMed PMID: 31425441.
  • Tragiannidis A, Herbrüggen H, Ahlmann M, Vasileiou E, Gastine S, Thorer H, Fröhlich B, Müller C, Groll AH. Plasma exposures following posaconazole delayed-release tablets in immunocompromised children and adolescents. J Antimicrob Chemother. 2019 Aug 27. pii: dkz359. doi: 10.1093/jac/dkz359.
  • Hagel S, Fiedler S, Hohn A, Brinkmann A, Frey OR, Hoyer H, Schlattmann P, Kiehntopf M, Roberts JA, Pletz MW; TARGET Study Group. Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomized controlled trial. Trials. 2019 Jun 6;20(1):330. doi: 10.1186/s13063-019-3437-x. PMID: 31171029; PMCID: PMC6554958.
  • Pea F, Krause R, Müller C, Hennart B, Richardson M, Meinitzer A, Wiesen MHJ, Wiktorowicz T, Spickermann J, Henriksen AS. Inter-laboratory analysis of Isavuconazole plasma concentration assays among European laboratories. TherDrugMonit. 2019 Mar 31. doi: 10.1097
  • Johannsen JO, Reuter H, Hoffmann F, Blaich C, Wiesen HJ, Streichert , Müller C. Reliable and easy-to-use LC-MS/MS-method for simultaneous determination of the antihypertensives Metoprolol, Amlodipine, Canrenone and Hydrochlorothiazide in patients with therapy-refractory arterial hypertension. JPBA. 2018, Supplementary material related to this article can be found, in the online version, at doi:https://doi.org/10.1016/j.jpba.2018.11.002.
  • Fietz C, Michels G, Müller C, Wiesen MHJ. Monitoring of apixaban in a super obese patient. Am J Med. 2018 Sep 7. pii: S0002-9343(18)30849-0. doi: 10.1016/j.amjmed.2018.08.021. [Epub ahead of print] PubMed PMID: 30201245.
  • Nies RJ, Müller C, Pfister R, Binder PS, Nosseir N, Nettersheim FS, Kuhr K, Wiesen MHJ, Kochanek M, Michels G. Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients. J Intensive Care. 2018 Sep 14;6:62. doi: 10.1186/s40560-018-0331-7. eCollection 2018. PubMed PMID: 30302254; PubMed Central PMCID: PMC6137863.
  • Müller C, Fietz C, Koehler P, Sibley G, Nforbugwe ACA, Streichert T, Wiesen MHJ. Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum. Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01356-18. doi: 10.1128/AAC.01356-18. Print 2018 Nov. PubMed PMID: 30150474.
  • Hackl A, Becker JU, Körner LM, Ehren R, Habbig S, Nüsken E, Nüsken KD, Ebner K, Liebau MC, Müller C, Pohl M, Weber LT. Mycophenolate mofetil following glucocorticoid treatment in Henoch-Schönlein purpura nephritis: the role of early initiation and therapeutic drug monitoring. Pediatr Nephrol. 2018 Apr;33(4):619-629. doi: 10.1007/s00467-017-3846-6. Epub 2017 Nov 25. PubMed PMID: 29177628.
  • Gastine S, Lehrnbecher T, Müller C, Farowski F, Bader P, Ullmann-Moskovits J, Cornely OA, Groll AH, Hempel G. Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children. Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01194-17. doi: 10.1128/AAC.01194-17. Print 2018 Jan. PubMed PMID: 29038273; PubMed Central PMCID: PMC5740334.
  • Müller C, Gehlen D, Blaich C, Prozeller D, Liss B, Streichert T, Wiesen MHJ. Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum. Ther Drug Monit. 2017 Oct;39(5):505-513. doi: 10.1097/FTD.0000000000000438. PubMed PMID: 28742650.
  • Strenger V, Farowski F, Müller C, Hofer N, Dornbusch HJ, Sperl D, Lackner H, Benesch M, Urban C. Low penetration of caspofungin into cerebrospinal fluid following intravenous administration of standard doses. Int J Antimicrob Agents. 2017 May 17. pii: S0924-8579(17)30159-0. doi: 10.1016/j.ijantimicag.2017.02.024. [Epub ahead of print] PubMed PMID: 28527634.
  • Wiesen MH, Blaich C, Streichert T, Michels G, Müller C. Paramagnetic micro-particles as a tool for rapid quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma by UHPLC-MS/MS. Clin Chem Lab Med. 2017 Mar 22. pii: /j/cclm.ahead-of-print/cclm-2016-0888/cclm-2016-0888.xml. doi: 10.1515/cclm-2016-0888. [Epub ahead of print] PubMed PMID: 28328524.
  • Wiesen MH, Blaich C, Müller C, Streichert T, Pfister R, Michels G. The Direct Factor Xa Inhibitor Rivaroxaban Passes Into Human Breast Milk. Chest. 2016 Jul;150(1):e1-4. doi: 10.1016/j.chest.2016.01.021. PubMed PMID: 27396794.
  • Hackl Á, Cseprekál O, Gessner M, Liebau MC, Habbig S, Ehren R, Müller C, Taylan C, Dötsch J, Weber LT. Mycophenolate Mofetil Therapy in Children With Idiopathic Nephrotic Syndrome: Does Therapeutic Drug Monitoring Make a Difference? Ther Drug Monit. 2016 Apr;38(2):274-9. doi: 10.1097/FTD.0000000000000258. PubMed PMID: 26488204.
  • Blaich C, Müller C, Michels G, Wiesen MH. Multi-analyte analysis of non-vitamin K antagonist oral anticoagulants in human plasma using tandem mass spectrometry. Clin Chem Lab Med. 2015 Nov;53(12):1981-90. doi: 10.1515/cclm-2014-1108. PubMed PMID: 25901716.
  • Linnerz K, Wiesen HJM, Blaich C, Junghaenel-Welzing S, Welzing L, Roth B and Müller C. Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Fentanyl and its Major Metabolite Norfentanyl in Critically Ill Neonates. J Chromatograph Separat Techniq 2015, S6
  • Hünseler C, Müller C, Roth B. The authors reply. Pediatr Crit Care Med. 2015 Jan;16(1):93-4. doi: 10.1097/PCC.0000000000000294. PubMed PMID: 25560291.
  • Bochennek K, Balan A, Müller-Scholden L, Becker M, Farowski F, Müller C, Groll AH, Lehrnbecher T. Micafungin twice weekly as antifungal prophylaxis in paediatric patients at high risk for invasive fungal disease. J Antimicrob Chemother. 2015 Jan 5. pii: dku544. [Epub ahead of print] PubMed PMID: 25564562.
  • Pfreundschuh M, Poeschel V, Zeynalova S, Hänel M, Held G, Schmitz N, Viardot A, Dreyling MH, Hallek M, Mueller C, Wiesen MH, Witzens-Harig M, Truemper L, Keller U, Rixecker T, Zwick C, Murawski N. Optimization of Rituximab for the Treatment of Diffuse Large B-Cell Lymphoma (II): Extended Rituximab Exposure Time in the SMARTE-R-CHOP-14 Trial of the German High-Grade Non-Hodgkin Lymphoma Study Group. J Clin Oncol. 2014 Nov 17. pii: JCO.2013.54.6861. [Epub ahead of print] PubMed PMID: 25403207.
  • Nosseir NS, Michels G, Binder P, Wiesen MH, Müller C. Simultaneous detection of ketamine, lorazepam, midazolam and sufentanil in human serum with liquid chromatography-tandem mass spectrometry for monitoring of analgosedation in critically ill patients. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 12;973C:133-141. doi: 10.1016/j.jchromb.2014.10.006. [Epub ahead of print] PubMed PMID: 25464106.
  • Nosseir NS, Michels G, Pfister R, Adam R, Wiesen MH, Müller C. [Therapeutic Drug Monitoring of antiinfectives in intensive care medicine]. Dtsch Med Wochenschr. 2014 Sep;139(38):1889-94. doi: 10.1055/s-0034-1387215. Epub 2014 Sep 9. Review. German. PubMed PMID: 25203549.
  • Hünseler C, Balling G, Röhlig C, Blickheuser R, Trieschmann U, Lieser U, Dohna-Schwake C, Gebauer C, Möller O, Hering F, Hoehn T, Schubert S, Hentschel R, Huth RG, Müller A, Müller C, Wassmer G, Hahn M, Harnischmacher U, Behr J, Roth B; Clonidine Study Group.. Continuous infusion of clonidine in ventilated newborns and infants: a randomized controlled trial. Pediatr Crit Care Med. 2014 Jul;15(6):511-22. doi: 10.1097/PCC.0000000000000151. PubMed PMID: 24751788.
  • Pfreundschuh M, Müller C, Zeynalova S, Kuhnt E, Wiesen MH, Held G, Rixecker T, Poeschel V, Zwick C, Reiser M, Schmitz N, Murawski N. Suboptimal dosing of rituximab in male and female patients with DLBCL. Blood. 2014 Jan 30;123(5):640-6. doi: 10.1182/blood-2013-07-517037. Epub 2013 Dec 2. PubMed PMID: 24297867.
  • Welzing L, Junghaenel S, Weiss V, Roth B, Mueller C, Wiesen MH. Disposition of midazolam in asphyxiated neonates receiving therapeutic hypothermia–a pilot study. Klin Padiatr. 2013 Dec;225(7):398-404. doi: 10.1055/s-0033-1358749. Epub 2013 Nov 28. PubMed PMID: 24288267.
  • Farowski F, Cornely OA, Vehreschild JJ, Wiesen M, Steinbach A, Vehreschild MJ, Müller C. Intracellular concentrations of anidulafungin in different compartments of the peripheral blood. Int J Antimicrob Agents. 2013 Apr;41(4):379-82. doi: 10.1016/j.ijantimicag.2012.12.002. Epub 2013 Jan 12. PubMed PMID: 23317969.
  • Würthwein G, Cornely OA, Trame MN, Vehreschild JJ, Vehreschild MJ, Farowski F, Müller C, Boos J, Hempel G, Hallek M, Groll AH. Population Pharmacokinetics of Escalating Doses of Caspofungin in a Phase II Study of Patients with Invasive Aspergillosis. Antimicrob Agents Chemother. 2013 Apr; 57(4):1664-71. doi: 10.1128/AAC.01912-12. Epub 2013 Jan 18. PubMed PMID: 23335740.
  • Körner RW, Müller C, Roth B, Vierzig A. Thiamin status of premature infants assessed by measurement of thiamin diphosphate in whole blood. Br J Nutr. 2012 Oct 1:1-8. [Epub ahead of print] PubMed PMID: 23020849
  • Döring M, Müller C, Johann PD, Erbacher A, Kimmig A, Schwarze CP, Lang P, Handgretinger R, Müller I. Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation. BMC Infect Dis. 2012 Oct 19;12:263.
  • Wiesen MH, Farowski F, Feldkötter M, Hoppe B, Müller C. Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device. J Chrom A 2012;1241:52-9
  • Müller C., Murawski N., Wiesen M., Held G., Poeschel V., Zeynalova S., Wenger M., Nickenig C., Peter N., Lengfelder E., Metzner B., Rixecker T., Zwick C., Pfreundschuh M., Reiser M. The role of gender and weight on rituximab clearance and serum elimination half life in elderly patients with DLBCL Jan. 2012, Blood 2012;119:3276-84
  • Farowski F, Cornely OA, Vehreschild JJ, Bauer T, Hartmann P, Steinbach A, Vehreschild MJ, Scheid C, Müller C. Intracellular concentrations of micafungin in different cellular compartments of the peripheral blood. Int J Antimicrob Agents. 2012 Mar;39(3):228-31.
  • Vehreschild J. J., Müller C., Farowski F., Vehreschild M.J.G.T., Cornely O.A., Fuhr U., Kreuzer K.-A., Hallek M., Kohl V., Factors Influencing Pharmacokinetics of Prophylactic Posaconazole Oral Suspension in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome Jan. EJCP-2011-0357.R2 Jan. 2012, accepted for publication in the European Journal of Clinical Pharmacology
  • Welzing L ES, Dlugay V, Wiesen MHJ, Roth B, Müller C. Remifentanil degradation in umbilical cord blood serum of preterm infants. Anesthesiology 2011 Mar; 114(3):570-7.
  • Farowski F, Cornely OA, Vehreschild JJ, Hartmann P, Bauer T, Steinbach A, Ruping MJ, Müller C. Intracellular concentrations of posaconazole in different compartments of peripheral blood. Antimicrob Agents Chemother 2010; 54:2928-31.
  • Farowski F, Cornely OA, Vehreschild JJ, Hartmann P, Bauer T, Steinbach A, Ruping MJ, Müller C. Quantitation of azoles and echinocandins in compartments of peripheral blood by liquid chromatography-tandem mass spectrometry. Antimicrob Agents Chemother 2010; 54:1815-9.
  • Kohl V, Müller C, Cornely OA, Abduljalil K, Fuhr U, Vehreschild JJ, Scheid C, Hallek M, Ruping MJ. Factors influencing pharmacokinetics of prophylactic posaconazole in patients undergoing allogeneic stem cell transplantation. Antimicrob Agents Chemother 2010; 54:207-12.
  • Rüping MJ, Müller C, Vehreschild JJ, Bohme A, Mousset S, Harnischmacher U, Frommolt P, Wassmer G, Drzisga I, Hallek M, Cornely OA. Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients. Mycoses 2009.
  • Körner RW, Vierzig A, Roth B, Müller C. Determination of thiamin diphosphate in whole blood samples by high-performance liquid chromatography–a method suitable for pediatric diagnostics. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877:1882-6.
  • Rüping MJ, Albermann N, Ebinger F, Burckhardt I, Beisel C, Müller C, Vehreschild JJ, Kochanek M, Fatkenheuer G, Bangard C, Ullmann AJ, Herr W, Kolbe K, Hallek M, Cornely OA. Posaconazole concentrations in the central nervous system. J Antimicrob Chemother 2008; 62:1468-70.
  • Störzinger D, Swoboda S, Lichtenstern C, Müller C, Weigand MA, Hoppe-Tichy T. Development and validation of a high-performance liquid chromatography assay for posaconazole utilizing solid-phase extraction. Clin Chem Lab Med 2008; 46:1747-51.
  • Hünseler C, Borucki D, Müller C, Hering F, Kremer W, Theisohn M, Roth B. Prospective evaluation of the pharmacodynamics of piritramide in neonates and infants. Eur J Pediatr 2008; 167:867-72.
  • Müller C, Kohl V, Farowski F, Cornely OA. [Posaconazole: another triazole antifungal of the new generation?]. Dtsch Med Wochenschr 2008; 133:2345-8.
  • Müller C, Ramic M, Harlfinger S, Hünseler C, Theisohn M, Roth B. Sensitive and convenient method for the quantification of clonidine in serum of pediatric patients using liquid chromatography/tandem mass spectrometry. J Chromatogr A 2007; 1139:221-7.
  • Müller C, Kremer W, Harlfinger S, Doroshyenko O, Jetter A, Hering F, Hünseler C, Roth B, Theisohn M. Pharmacokinetics of piritramide in newborns, infants and young children in intensive care units. Eur J Pediatr 2006; 165:229-39.
  • Müller C, Arndt M, Queckenberg C, Cornely OA, Theisohn M. HPLC analysis of the antifungal agent posaconazole in patients with haematological diseases. Mycoses 2006; 49 Suppl 1:17-22.
  • Langenfeld S, Birkenfeld L, Herkenrath P, Müller C, Hellmich M, Theisohn M. Therapy of the neonatal abstinence syndrome with tincture of opium or morphine drops. Drug Alcohol Depend 2005; 77:31-6.
  • Dagtekin O, Marcus H, Müller C, Böttiger BW, Spöhr F. Lipid therapy for serotonin syndrome after intoxication with venlafaxine, lamotrigine and diazepam. Minerva Anestesiol. 2011 Jan;77(1):93-5. Epub 2010 Nov 10.
  • Müller C, Reuter H, Dohmen C. Intoxication after extreme oral overdose of quetiapine to attempt suicide: pharmacological concerns of side effects. Case Report Med 2009; 2009:371698.