General information:
Substance group: Antidepressant, selective serotinin reuptake inhibitor ATC: N06AB04
Trade names: Citalopram-*®, Cipramil®, Citalon®, Sepram®
available dosages: film tablets 10 / 20 / 30 / 40 mg, solution for oral 20 mg/mL,
Solution 40 mg/mL injection
Reference ranges:
50 – 110 µg/L
Toxic plasma mirrors: from 220 µg/L
Sampling:
Material: Serum (Monovette brown) Minimum volume for analysis: 500µl
Recommendation: trough level (directly before the next intake)
Requirement (internal): … requirement (external):
Analytics:
Test principle: liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)
Protein precipitation with acetonitrile, chromatographic separation, mass spectrometry
Analysis according to mass charge ratio
Analysis system: triple stage Quadrupol mass spectrometer (LC-MS/MS)
Findings release: on the same working day, via LIMS
DrugBank: https://go.drugbank.com/drugs/DB00215